Prior online health research has mainly focused on the predictors or outcomes of online health information, leaving online health information itself understudied. Therefore, online health information has remained an umbrella term encompassing different platforms (expert- vs. peer-generated). A hybrid method that combines qualitative and computational methods is used to identify different topics discussed on these different platforms, and an initial model of patients’ social support needs was developed and applied to data obtained from the hybrid method. Using topic modeling (Nposts = 52.990), topics on two expert- and two peer-generated platforms were identified. Differences between and within platforms were found. While peer-generated platforms mainly covered interaction on emotional support topics, expert-generated platforms covered informational topics. Within peer-generated platforms, patients used their experiences differently.